THE MECHANISMS OF DISINHIBITION (MoD) LABORATORY
Director: Arielle Baskin-Sommers, Ph.D.
Disinhibition is central to many conceptualizations of psychopathology (e.g., substance abuse, psychopathy, externalizing [antisocial personality, low constraint]) and can be expressed in different ways from impulsivity to criminality to decision-making deficits. Although many syndromes of disinhibition display similar behaviors (e.g., impulsivity, aggression, antisocial behavior, substance use), the cognitive-affective deficits associated with each are relatively distinct. Research in the MoD Lab utilizes interdisciplinary theoretical principles and methods (e.g., electrophysiology, neuroimaging, self-report) to distinguish the deficits associated with these phenotypically similar syndromes in order to improve the identification of these syndromes and develop innovative syndrome-specific interventions. To the extent that we can identify and specify the pre-disposing mechanisms associated with disinhibited syndromes and conceptualize their impact on behavior, we are poised to unravel the problem of disinhibitory psychopathology.
General Research Interests
- Interactions among selective attention, executive functions, and emotion in disinhibition
- Etiopathogenesis of Psychopathy, Antisocial Behavior, and Substance Use Disorders
- Psychophysiological and neural correlates of impulsivity, poor constraint, and externalizing
- Individual differences in attention to context and affective cognitive control
- Cognitive-affective functions in Personality Disorders and Traits
- Development of mechanism-matched cognitive remediation strategies for disinhibition